Biosynergy
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Your Partner for Development and Production of Biologics



Monoclonal Antibody Production

Our senior personnel have over 20 years experience in the contract manufacture of biological products, creation of cell lines and production of monoclonal antibodies. Many of our contracts have led to marketed products.

Our cell culture facility offers access to fifteen continuous perfusion bioreactors utilizing disposable hollow fibre technology-based flow paths and can provide a range of cell culture services to meet the needs of biomedical researchers, drug discovery companies, immunodiagnostics manufacturers and suppliers of monoclonal antibodies and recombinant proteins.

At Biosynergy (Europe) the core expertise is in provision of mammalian cell culture services and process development, but we also have a dedicated microbial cell culture suite. We offer a range of services for the development and pre-clinical scale-up of pipeline biotherapeutic proteins. Our multi-product manufacturing facility allows us to service the needs of a wide range of clients simultaneously whilst maintaining proper segregation of each product line.

Our protein purification team has a wide range of experience with monoclonal antibodies, antibody fragments and recombinant proteins and routinely purifies multi-gram batches of monoclonal antibody.

Our primary antibody production and biomanufacturing platform is hollow fibre bioreactor technology (HFBR), a cell culture technique suitable for the production of multi-gram quantities of mammalian cell-derived biomolecules within a multi-client contract manufacturing facility.

Finished products are formulated and supplied to your specifications and requirements in accordance with best manufacturing practices. Our expertise spans a range of activities associated with process development and production of new bio-products and includes

  • Development of high secreting MAb clones
  • Cell line characterisation and cell banking
  • Cell fusion and cloning
  • Cell culture in hollow fibre bioreactors
  • Downstream processing
  • Assay development for a range of molecules
We have a great depth of knowledge in the project management of new product development programmes for immunodiagnostic and bio-therapeutic applications.
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