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From Clone to Clinic - Your First
Choice Manufacturer
| Q |
How much
will it cost to produce 1gm, 10gm, 100gm of purified protein? |
| A |
Accuracy of costing is directly
proportional to information available on the cell line
to be used.
Our short evaluation programme (4-8 weeks) will provide
a detailed report on the cell line and its suitability
for production. From this information we will provide
an accurate costing and timescale for completion of your
project.
Downstream processing protocols also affect yield, and
for monoclonal antibodies requiring a Protein A purification
step, antibody subclass will affect recovery levels.
Talk to us about process development and optimisation
before embarking on production campaigns. |
| Q |
Is it
possible to start production within 4 weeks? |
| A |
Yes. Subject to sufficient
information being available.
Download, complete and return our customer questionnaire
to enable us to give you the answer. |
| Q |
Is my
cell line suitable for manufacture for clinical trials? |
| A |
Refer to our project progression
schedule. Is the cell line sufficiently well characterised
(stability, sterility, biosafety considerations). Unsure?
Talk to us or go to links and talk to BioReliance |
| Q |
Being
a multi-client, multi-product facility, can you assure
confidentiality? |
| A |
Yes. Our secure document archiving
systems ensure that no breach of confidence occurs. Client
and project confidentiality is a core business ethic. |
| Q |
How do
I know if my cell line is stable? |
| A |
Cell lines often contain low
or non secreting variants.
High level expression of such variants during long term
culture is undesirable.
We will assess your line and generate a cell bank suitable
for long term production. Where possible we will select
high secreting clones as part of this process, thereby
reducing production time. |
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