About us Mammalian cell culture Microbial cell culture Downstream processing Assay development FAQS Links Contact us
newslink


Over 20 years of experience in contract manufacturing of biological products, producing cell lines and monoclonal antibodies, some of which are now marketed products.

Our cell culture team currently operates seventeen continuous perfusion bioreactors and can provide a range of cell culture techniques to meet the needs of biomedical researchers, drug discovery companies, immunodiagnostics manufacturers and suppliers of monoclonal antibodies and recombinant proteins. Whilst the core expertise is in provision of mammalian cell culture services and process development, we also have a dedicated microbial cell culture suite. Our experience of working with drug discovery companies also allows us to offer a range of services for the development and pre-clinical scale-up of biotherapeutic proteins. A multi-product manufacturing facility allows us to service the needs of a wide range of clients simultaneously whilst maintaining proper segregation of each product line.

Our protein purification team has a wide range of experience with monoclonal antibodies, antibody fragments and recombinant proteins and routinely purifies 10-40 gram batches of monoclonal antibody.

Our primary antibody production and biomanufacturing platform is hollow fibre bioreactor technology (HFBR), a cell culture technique suitable for production of multi-gram quantities of mammalian cell-derived biomolecules within a multi-client contract manufacturing facility. We have developed and now operate our own HFBR system, enabling clients to benefit from our lower production costs.

Finished products can be formulated and supplied to your specifications and requirements with the knowledge that the material has been produced in accordance with the best manufacturing practices.

A total commitment to client and project is the essence of our successful customer service record from first contact to project completion.

Our expertise spans a range of activities associated with process development and production of new bio-products and includes:

Development of high secreting MAb clones
Cell line characterisation and cell banking
Fusions and clonings
Cell culture in hollow fibre bioreactors
Downstream processing
Assay development for a range of molecules
Project management of new product development programmes for diagnostic and bio-therapeutic applications

Our clients span diagnostic, pharmaceutical and biotechnology companies. Contact us for details if you require references.