|
|
Over 20 years of experience in
contract manufacturing of biological products, producing cell
lines and monoclonal antibodies, some of which are now marketed
products.
Our cell culture team currently operates seventeen continuous
perfusion bioreactors and can provide a range of cell culture
techniques to meet the needs of biomedical researchers, drug
discovery companies, immunodiagnostics manufacturers and suppliers
of monoclonal antibodies and recombinant proteins. Whilst
the core expertise is in provision of mammalian cell culture
services and process development, we also have a dedicated
microbial cell culture suite. Our experience of working with
drug discovery companies also allows us to offer a range of
services for the development and pre-clinical scale-up of
biotherapeutic proteins. A multi-product manufacturing facility
allows us to service the needs of a wide range of clients
simultaneously whilst maintaining proper segregation of each
product line.
Our protein purification team has a wide range of experience
with monoclonal antibodies, antibody fragments and recombinant
proteins and routinely purifies 10-40 gram batches of monoclonal
antibody.
Our primary antibody production and biomanufacturing platform
is hollow fibre bioreactor technology (HFBR), a cell culture
technique suitable for production of multi-gram quantities
of mammalian cell-derived biomolecules within a multi-client
contract manufacturing facility. We have developed and now
operate our own HFBR system, enabling clients to benefit from
our lower production costs.
Finished products can be formulated and supplied to your specifications
and requirements with the knowledge that the material has
been produced in accordance with the best manufacturing practices.
A total commitment to client and project is the essence of
our successful customer service record from first contact
to project completion.
Our expertise spans a range of
activities associated with process development and production
of new bio-products and includes:
 |
Development of high secreting MAb clones |
 |
Cell line characterisation and cell banking |
 |
Fusions and clonings |
 |
Cell culture in hollow fibre bioreactors |
 |
Downstream processing |
 |
Assay development for a range of molecules |
 |
Project management of new product development
programmes for diagnostic and bio-therapeutic applications |
Our clients span diagnostic, pharmaceutical and biotechnology
companies. Contact us for details if you require references.
|
|
|